Aging and cancer: molecular facts and awareness for Turkey

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GÜNDÜZ G., FIŞKIN K.

TURKISH JOURNAL OF BIOLOGY, cilt.38, sa.6, ss.708-719, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 38 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3906/biy-1405-9
  • Dergi Adı: TURKISH JOURNAL OF BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.708-719
  • Anahtar Kelimeler: Biological aging, cancer, molecular mechanisms, environmental factors, age-related cancer characteristics, epidemiology, Turkey, OXIDATIVE STRESS, SENESCENCE, LINK
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Two important subjects concerning extension of the human life-span are biological aging processes and their relationship to diseases, and especially to the formation of cancer. It is clear that an aging population poses some challenges for developing countries. We set out to show the demographic structure of Turkey and to discuss the feasibility of decreasing the prevalence of cancer. We overviewed the literature on the relationship between biological aging and cancer formation, the environmental causes of cancer, and age-related characteristics of cancer in the elderly. In addition, some statistical data on the changing demography of Turkey were reviewed. It is seen that some predictions and preliminary preparations should be taken. However, in order to take precautions, first of all there must be a holistic approach from the causes to the consequences.