Ezrin is a key element in the human vagina

Fadiel A., Lee H. H., DEMİR N., Richman S., Iwasaki A., Connell K., ...Daha Fazla

MATURITAS, cilt.60, sa.1, ss.31-41, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 60 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.maturitas.2008.03.007
  • Dergi Adı: MATURITAS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.31-41
  • Anahtar Kelimeler: ezrin, MERM, pelvic floor, vaginal cycle, estrogen, ovarian cycle, HRT, MARSUPIAL MONODELPHIS-DOMESTICA, ELECTRON-MICROSCOPY, ESTROUS-CYCLE, ERM PROTEINS, EPITHELIUM, PERMEABILITY, RECEPTOR, COMPLEX, MOESIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: The vagina is a complex tubular structure that has reproductive, support and barrier functions. These depend on the cytoarchitecture of the vaginal cells, which is controlled by key proteins. Cytoskeletal proteins determine cell polarity and membrane specializations by integrating the actin cytoskeleton with cell membranes. This integration is the domain of cytoskeletal proteins including the MERM protein family (moesin-ezrin-radixin-Merlin). Nothing is known about the cyto-localization of the MERM's in the vaginal epithelium or how it influences the cytoarchitecture of the vaginal epithelium and stroma.