Late relapse of testicular cancer: Recurrence after 24 years and treatment with chemotherapy alone

Akar E., Tural D., Arslan D., BAŞSORGUN C. İ., Yildiz O.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, cilt.11, sa.3, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4103/0973-1482.137915
  • Dergi Adı: JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Late relapse, nonseminoma, salvage chemotherapy, seminoma, testicular cancer, GERM-CELL TUMORS, CISPLATIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Late relapse of testicular cancer, defined as >2 years interval between initial treatment and recurrence, is a rare disease with the incidence rate of 2.6%. Due to its chemoresistant features, treatment options of late relapses are controversial while surgical approach and cisplatin-based chemotherapies can be considered. We report here a patient with nonseminomatous germ cell tumor who experienced relapse 24 years after his first diagnosis. After detecting left supraclavicular lymphadenopathy and absence of any other malignant lesion in positron emission tomography-computerized tomography, patient was treated with three cycles of VeIP regimen (vinblastine/ifosfamide/cisplatin). Second complete response to this treatment was achieved with chemotherapy alone.