Low serum copeptin levels in patients with obstructive sleep apnea


Ozben S., Guvenc T. S., Huseyinoglu N., Sanivar H. S., Hanikoglu F., Cort A., ...Daha Fazla

SLEEP AND BREATHING, cilt.17, sa.4, ss.1187-1192, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s11325-013-0822-7
  • Dergi Adı: SLEEP AND BREATHING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1187-1192
  • Anahtar Kelimeler: Obstructive sleep apnea, Copeptin, Antidiuretic hormone, Cardiovascular diseases, ATRIAL-NATRIURETIC-PEPTIDE, POSITIVE AIRWAY PRESSURE, RISK, VASOPRESSIN, HEMORRHAGE, POLYURIA, TROPONIN, NOCTURIA, ADULTS, MEN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Copeptin, the C-terminal fragment of antidiuretic hormone (ADH), is a new biomarker that has been found to be elevated in several cardiovascular disorders and is related with prognosis. Patients with obstructive sleep apnea demonstrate a tendency to develop coronary and cerebral atherosclerotic disease. Our aim was to investigate copeptin levels in untreated new diagnosed obstructive sleep apnea patients without manifest cardiovascular disorders in order to determine whether copeptin could be used as a biomarker in this group.