Oxidative Status in Epileptic Children Using Carbamazepine

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Tutanc M., Aras M., Dokuyucu R., Altas M., Zeren C., Arica V., ...Daha Fazla

IRANIAN JOURNAL OF PEDIATRICS, cilt.25, sa.6, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5812/ijp.3885
  • Dergi Adı: IRANIAN JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Carbamazepine, Antioxidant Capacity, Oxidant Status, TOTAL ANTIOXIDANT CAPACITY, OXYGEN-FREE-RADICALS, ANTIEPILEPTIC DRUGS, LIPID-PEROXIDATION, PASSIVE SMOKING, TRACE-ELEMENTS, REDOX STATUS, STRESS, GLUTATHIONE, DYSFUNCTION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: There is an increasing attention towards the relationship between oxidative stress and epilepsy. The effect of antiepileptic drugs on oxidant status is of major interest. Antiepileptic drugs can increase levels of free radicals, which consequently might lead to seizures. Carbamazepine (CBZ) is an antiepileptic drug commonly used in childhood and adolescence.