COVID-19 spreading across world correlates with C677T allele of the methylenetetrahydrofolate reductase (MTHFR) gene prevalence

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Ponti G., Pastorino L., Manfredini M., Ozben T., Oliva G., Kaleci S., ...Daha Fazla

JOURNAL OF CLINICAL LABORATORY ANALYSIS, cilt.35, sa.7, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 7
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1002/jcla.23798
  • Dergi Adı: JOURNAL OF CLINICAL LABORATORY ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Analytical Abstracts, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Anahtar Kelimeler: C677 T mutation prevalence, COVID-19 vulnerability, Homocysteine, MTHFR gene, HYPERHOMOCYSTEINEMIA, HOMOCYSTEINE, FREQUENCIES
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: Homocysteine assessment has been proposed as a potential predictive biomarker for the severity of COVID-19 infection. The purpose of this review was to analyze the correlation between the prevalence of MTHFR C677 T gene polymorphism and COVID-19 incidence and mortality worldwide.