The effects of non-surgical periodontal therapy on neutrophil elastase and elastase alpha-1 proteinase inhibitor levels in GCF in periodontitis patients with or without acute coronary syndrome

KAYAR N. A., ÜSTÜN K., Gozlu M., Haliloglu S., Alptekin N. O.

CLINICAL ORAL INVESTIGATIONS, cilt.25, sa.5, ss.3329-3338, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s00784-021-03838-3
  • Dergi Adı: CLINICAL ORAL INVESTIGATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.3329-3338
  • Anahtar Kelimeler: Non-surgical periodontal therapy, Acute coronary syndrome, Neutrophil elastase, Alpha-1 proteinase inhibitor
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective Periodontitis may contribute to vascular damage, resulting in the destabilization of atherosclerotic plaque leading to acute coronary syndrome (ACS). In this study, we explored the effect of non-surgical periodontal treatment (NSPT) on cardiovascular blood biomarkers and gingival crevicular fluid (GCF) neutrophil elastase (NE) and alpha 1-proteinase inhibitor (alpha-1PI) levels in periodontitis (P) participants with and without ACS.