Triamcinolone up-regulates GLUT 1 and GLUT 3 expression in cultured human placental endothelial cells

Kipmen-Korgun D., Ozmen A., Unek G., ŞİMŞEK M., Demir R., KORGUN E. T.

CELL BIOCHEMISTRY AND FUNCTION, cilt.30, sa.1, ss.47-53, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1002/cbf.1817
  • Dergi Adı: CELL BIOCHEMISTRY AND FUNCTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.47-53
  • Anahtar Kelimeler: glucocorticoids, glucose transport, pregnancy, fetal growth, GLUCOSE-TRANSPORTER EXPRESSION, GLUCOCORTICOID-RECEPTOR, PROTEIN EXPRESSION, INSULIN-RESISTANCE, FETAL-GROWTH, DEXAMETHASONE, EXPOSURE, SYNCYTIOTROPHOBLAST, DECIDUALIZATION, IMPLANTATION
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The placenta is a glucocorticoid target organ, and glucocorticoids (GCs) are essential for the development and maturation of fetal organs. They are widely used for treatment of a variety of diseases during pregnancy. In various tissues, GCs have regulated by glucose transport systems; however, their effects on glucose transporters in the human placental endothelial cells (HPECs) are unknown.