SERUM GLYCATED LIPOPROTEINS IN TYPE-II DIABETIC-PATIENTS WITH AND WITHOUT COMPLICATIONS

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YEGIN A., OZBEN T.

ANNALS OF CLINICAL BIOCHEMISTRY, cilt.32, ss.459-463, 1995 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32
  • Basım Tarihi: 1995
  • Doi Numarası: 10.1177/000456329503200505
  • Dergi Adı: ANNALS OF CLINICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.459-463
  • Anahtar Kelimeler: GLYCATED VLDL, DIABETIC RETINOPATHY, DIABETIC NEUROPATHY, HYPERTENSION, LOW-DENSITY-LIPOPROTEIN, MONOCYTE-DERIVED MACROPHAGES, CHOLESTERYL ESTER SYNTHESIS, DEPENDENT DIABETICS, APOLIPOPROTEINS, LIPIDS, GLYCOSYLATION, FRUCTOSAMINE, HEMOGLOBIN, DISEASE
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The extent of lipoprotein glycation was assessed in 82 patients diagnosed as diabetes mellitus type II. Glycated lipoprotein levels in serum were determined by agarose gel film electrophoresis in 48 non-diabetic control subjects, 56 diabetics with complications and 26 diabetics with no complications. All glycated lipoproteins were higher in the patients when the diabetics were compared to the control group, but glycated very low-density lipoprotein (VLDL) was the only glycated lipoprotein fraction that was observed to be higher in the diabetic patients with complications compared to the patients without complications (P < 0.01). Triglycerides and VLDL-cholesterol were also increased in the diabetics, but there was no significant difference in these variables when the patients without complications were compared to the control subjects. There was no difference in total cholesterol and low-density lipoprotein (LDL)-cholesterol levels of the diabetic patients compared to the controls.