Urinary 8-isoprostane levels can indicate the presence, severity and extent of angiographic coronary artery disease

BAŞARICI İ., Altekin R. E., Demir I., Yilmaz H.

ACTA CARDIOLOGICA, cilt.63, sa.4, ss.415-422, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.2143/ac.63.4.2033038
  • Dergi Adı: ACTA CARDIOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.415-422
  • Anahtar Kelimeler: oxidative stress, isoprostone, atherosclerosis, coronary artery disease, Gensini score, C-REACTIVE PROTEIN, OXIDATIVE STRESS, HEART-DISEASE, 8-ISO-PROSTAGLANDIN F2-ALPHA, PLASMA F-2-ISOPROSTANES, CARDIOVASCULAR-DISEASE, DENSITY-LIPOPROTEIN, LIPID-PEROXIDATION, VULNERABLE PATIENT, RISK-ASSESSMENT
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background-Atherosclerotic coronary artery disease is the leading cause of death worldwide. Oxidative stress is one of the key elements in the pathogenesis of atherosclerosis. Isoprostanes are established markers of oxidative stress. The aim of this study was to investigate the association of urinary 8-isoprostane levels with the presence and severity of coronary artery disease (CAD) assessed by a validated scoring system.