Disseminated Cryptococcosis With Severe Increased Intracranial Pressure Complicated With Cranial Nerve Palsy in a Child.

Aldemir Kocabaş B., Emin Parlak M., Özhak Baysan B., Karaali K., Bingöl A., Haspolat Ş.

The Pediatric infectious disease journal, cilt.37, ss.373-375, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1097/inf.0000000000001765
  • Dergi Adı: The Pediatric infectious disease journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.373-375
  • Anahtar Kelimeler: cryptococcosis, meningitis, increased intracranial pressure, interferon gamma, MENINGITIS, MANAGEMENT, NEOFORMANS, THERAPY
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Cryptococcosis is less common in children than in adults but remains an important cause of pneumonia and meningoencephalitis in both immunocompromised and immunocompetent patients. Intracranial hypertension commonly complicates cryptococcal meningitis and may cause significant visual and neurologic morbidity and mortality. Early and aggressive management of intracranial hypertension in accordance with established guidelines reduces the risk of long-term complications and death. In this case report, we present a 12-year-old girl with cryptococcal meningitis, pneumonitis and dermatitis complicated with cranial nerve palsy and loss of vision. She was successfully treated with serial cerebrospinal fluid drainage, antifungal and interferon gamma therapy.