The Necessity of Cytoreductive Nephrectomy in Patients With Metastatic Renal Cell Carcinoma Using Antiangiogenic Targeted Therapy After Interferon Alfa-2b

Mutlu H., Gunduz S., Buyukcelik A., Yildiz O., Uysal M., Tural D., ...Daha Fazla

CLINICAL GENITOURINARY CANCER, cilt.12, sa.6, ss.447-450, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.clgc.2014.06.006
  • Dergi Adı: CLINICAL GENITOURINARY CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.447-450
  • Anahtar Kelimeler: Angiogenesis, Nephrectomy, Prognosis, Renal cell cancer, Survival, ERA, SURVIVAL, CANCER, IMPACT, ALPHA
  • Akdeniz Üniversitesi Adresli: Evet

Özet

The effects of cytoreductive nephrectomy (CRN) on prognosis of patients with metastatic renal cell cancer (RCC) using antiangiogenic targeted agents were evaluated. The median overall survival was significantly higher in the group that received CRN (P = .034). We speculate that CRN is still an important part of treatment modalities in patients with metastatic RCC in modern era targeted therapy, which is currently the best systemic therapy.