Potassium channels in the vasodilating action of levosimendan on the human umbilical artery

YILDIZ O., Nacitarhan C., SEYREK M.

JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, cilt.13, sa.4, ss.312-315, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 4
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.jsgi.2006.02.005
  • Dergi Adı: JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.312-315
  • Anahtar Kelimeler: human umbilical artery, levosimendan, potassium channels, smooth muscle, HEART-FAILURE, CALCIUM SENSITIZER, PORTAL-VEIN, RELAXATION, INODILATOR, OUTPUT, DRUG
  • Akdeniz Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Levosimendan is a calcium-sensitizing agent and inodilator working via potassium channels, which is under current investigation in the treatment of heart failure. We investigated the type of potassium channels that play a role on the dilatating effect of levosimendan on the contractile tones of the isolated human umbilical artery (HUA).