Effect of ER stress on sphingolipid levels and apoptotic pathways in retinal pigment epithelial cells

Afsar E., KIRIMLIOĞLU E., ÇEKER T., YILMAZ C., DEMİR N., Aslan M.

REDOX BIOLOGY, cilt.30, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.redox.2020.101430
  • Dergi Adı: REDOX BIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE, MEDLINE, Directory of Open Access Journals
  • Anahtar Kelimeler: Sphingolipid, Tunicamycin, Retinal pigment epithelial cells, ENDOPLASMIC-RETICULUM STRESS, UNFOLDED PROTEIN RESPONSE, CERAMIDE, ACTIVATION, DEATH, CERAMIDE-1-PHOSPHATE, SYNTHASE, CALPAIN
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Background: We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress.