Primary diffuse large B-cell lymphoma of maxillary sinus: Case report and literature


Stevanovıc Sancar B., Semerci Z. M., Günen Yılmaz S., Derin A. T., Özbilim G.

American journal of diagnostic imaging, cilt.9, sa.2, ss.16-22, 2023 (Hakemli Dergi)

Özet

Background: Diffuse large B-cell lymphoma (DLBCL) is the most common type of malignant lymphoma, accounting for 30%–40% of non-Hodgkin lymphoma (NHL) cases in adults. A specific type of NHL, primary paranasal sinus lymphoma, is a rare neoplasm of extranodal NHL and can often be difficult to diagnose. It generally has a poor prognosis because of the complex anatomy of the region and it can usually be noticed at an advanced stage. Case Presentation: In this case report, we present DLBCL of the maxillary sinus in a patient who attended to our clinic with a complaint of swelling in the maxillary anterior region for 3 months. Before coming to our clinic, the patient was examined by several physicians who misdiagnosed her condition as a lack of additional imaging methods and incomplete examination, assuming dental origin of lesion. After radiological evaluations and histopathological examination the correct diagnosis was made and the patient was referred to the hematology clinic where chemotherapy was planned. Conclusion: Despite the advancement of modern diagnostic methods, timely recognition of disease symptoms still forms the basis of early diagnosis. This case report demonstrates the need for systematic examination of anatomical structures during clinical and radiographic evaluation in terms of early diagnosis and to prevent delays in treatment