The effect of electroconvulsive therapy on neutrophyl/lymphocyte ratio

Canan F., Kurklu N., Gecici O., Kuloglu M.

JOURNAL OF MOOD DISORDERS, cilt.6, sa.1, ss.1-6, 2016 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5455/jmood.20160218093328
  • Dergi Adı: JOURNAL OF MOOD DISORDERS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1-6
  • Anahtar Kelimeler: electroconvulsive therapy, neutrophil/lymphocyte ratio, inflammation, immunology, NEUTROPHIL-LYMPHOCYTE RATIO, NEUTROPHIL/LYMPHOCYTE RATIO, BIPOLAR DISORDER, IMMUNE FUNCTION, HIPPOCAMPUS, DEPRESSION, CYTOKINES, SYSTEM, SHOCK, ECT
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: Inflammatory and immune mechanisms are reported to play important roles in the pathophysiology of psychiatric disorders. Electroconvulsive therapy (ECT) is regarded as an effective treatment of not only depression, but also schizophrenia and mania, especially when there is no response to pharmacological interventions. Despite the common use of ECT, its mechanism of action is mostly unknown. Few studies examined the effect of ECT on inflammatory and immune functions. The neutrophillymphocyte ratio (NLR) is a simple and easily accessible indicator of the systemic inflammatory response. Our aim was to investigate whether a series of ECT sessions would change NLR in patients with major depression, bipolar disorder, or schizophrenia.