Tranexamic Acid and Hyaluronate/Carboxymethylcellulose Create Cell Injury

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Yildiz E., Yilmaz B., Dilbaz S., Ustun Y., Kumru S.

JSLS-JOURNAL OF THE SOCIETY OF LAPAROENDOSCOPIC SURGEONS, cilt.18, sa.3, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4293/jsls.2014.00044
  • Dergi Adı: JSLS-JOURNAL OF THE SOCIETY OF LAPAROENDOSCOPIC SURGEONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Adhesion, Hyaluronate/carboxymethylcellulose, Rat, Tranexamic acid, Uterine horn, POSTOPERATIVE ADHESION FORMATION, UTERINE HORN MODEL, RAT MODEL, PREVENTION, REDUCTION, MELATONIN, PRODUCT
  • Akdeniz Üniversitesi Adresli: Hayır

Özet

Background and Objectives: Postoperative pelvic adhesions are associated with chronic pelvic pain, dyspareunia, and infertility. The aim of this study was to evaluate the adhesion prevention effects of tranexamic acid (TA) and hyaluronate/carboxymethylcellulose (HA/CMC) barrier in the rat uterine horn models on the basis of macroscopic and microscopic adhesion scores and histopathological as well as biochemical parameters of inflammation.