Single Optical Fiber Probe Spectroscopy for Detection of Dysplastic Tissues

CANPOLAT M., Denkceken T., AKMAN KARAKAŞ A., ALPSOY E., Tuncer R., AKYÜZ M., ...Daha Fazla

22nd International Conference on Nonlinear Dynamics of Electronic Systems (NDES), Albena, Bulgaristan, 4 - 06 Temmuz 2014, cilt.438, ss.349-354 identifier identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası: 438
  • Doi Numarası: 10.1007/978-3-319-08672-9_41
  • Basıldığı Şehir: Albena
  • Basıldığı Ülke: Bulgaristan
  • Sayfa Sayıları: ss.349-354
  • Anahtar Kelimeler: Single-scattering spectroscopy, Cancer, Diagnosis, Non-invasive, Real-time, SCATTERING SPECTROSCOPY, LIGHT-SCATTERING, CELLS
  • Akdeniz Üniversitesi Adresli: Evet

Özet

A single optical fiber probe with a core diameter of 100 mu m was used to deliver visible light to tissue and from tissue to a spectrometer to diagnose cancerous tissues of different organs. Measurements were performed on brain, skin, cervix and prostate tumor specimens and surrounding normal tissues ex-vivo. The spectral slopes were positive for normal tissues and negative for the tumors. Signs of the spectral slopes were used as a discrimination parameter to differentiate tumor from normal tissues for the four organ tissues. Sensitivity and specificity of the system in differentiation between tumors from normal tissues were 93% and % 100 for brain, 87% and 85% for skin, 93.7% and 46.1% for cervix and 98% and 100% for prostate respectively.