The Value Of Ultra-Sensitive Troponin-I In Determining Mortality In Patients With Suspected Acute Coronary Syndrome


Aracı Ç. E., DUYAN M., KARTAL M., Göksu E.

Akdeniz Tıp Dergisi, cilt.9, sa.3, ss.265-270, 2023 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 3
  • Basım Tarihi: 2023
  • Doi Numarası: 10.53394/akd.1032104
  • Dergi Adı: Akdeniz Tıp Dergisi
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.265-270
  • Akdeniz Üniversitesi Adresli: Evet

Özet

Objective: This study investigated the role of the reference value of ultra-sensitive troponin kits used in daily practice in determining mortality. Material and Methods: This study was conducted in the emergency department (ED) of Akdeniz University Hospital between January 1 2018 and June 30 2019. All patients admitted to the emergency department within a period of eighteen months and who had the result of the ultra-sensitive troponin level in the range of 0.06-0.1 ng/mL were included in the study. The recurrent admissions of the patients to the ED were included, and only the first troponin values of the patients were taken as s reference for the study. Results: It was determined that 1029 troponin values of 591 patients with initial troponin I value in the range 0.06-0.1 ng/mL were measured. It was found that 332 of these patients were discharged from the emergency department, and the others were hospitalized. It was found that 168 (28.43%) of the patients died. Considering the gender distribution of the patients who died, it was observed that 101 (60.11%) patients were male, and 67 (39.89%) patients were female. A statistically significant difference was found between the ages of the patients who died (mean 71.38±12.25) and the age of patients alive (mean 61.78 ± 15.89) (p <0.019). In univariate analysis, in addition to the positive troponin value, DM (p<0.022) and hyperlipidemia (p<0.018) were found to be statistically significant. Conclusion: For high-sensitive troponin worked in the ED, the upper value of 0.06 ng/mL effectively determines mortality.